Work

Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis

Year: 2025

Type: article

Abstract: Toxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life-threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41-year-old female known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection of diffuse pustular and hemorrhagic crusted lesions with immediate antifungal treatment in TEN is crucial to prevent systemic complications and enhance patient outcomes.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71451

Authors: Saman Al‐Zahawi, Fatemeh Saberi, Tahereh Soori, Elham Yousefi, Kamran Balighi

Institutions: Razi Hospital, Razi Hospital, Tehran University of Medical Sciences

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820