Evaluation of effect of transfusion practices on infection risks in open heart surgery: Insights from a study at Amir-Al-Mominin Hospital in Golestan province, Iran, 2022
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: Coronary artery bypass graft surgery (CABG) is the standard treatment for obstructive coronary artery disease, particularly in patients with multi-vessel involvement or diabetes. Blood transfusions are often necessary during CABG, with rates ranging from 40% to 90%. We studied the multifactorial analysis of transfusion practices and infection risks in open heart surgery in Golestan Province, Iran. Methods: In the study we reviewed the medical records of 268 patients who underwent open heart surgery in 2022. Exclusion criteria included known immunodeficiency conditions, immunosuppressive drug use, and incomplete records. Data on risk factors (age, gender, diabetes, BMI, smoking) and laboratory results (CRP, WBC, blood cultures) were collected. Results: =0.047). PC transfusion occurred in 29.5% of patients, with no significant differences between diabetic and non-diabetic groups. Conclusion: The prevalence of positive blood cultures, particularly among diabetic patients, emphasizes the importance of vigilant monitoring and management of this population to mitigate infection risks.
Authors: Seyedeh Sedigheh Hosseini, Fatemeh Tahmasebi, Mohammad Taher Hojjati, Mahdi Zahedi, Sima Besharat
Institution: Golestan University of Medical Sciences
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416538615
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