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Pediatric diarrhea management with probiotics supplementation: Results from a randomized controlled trial

Year: 2025

Type: article

Study design: Clinical Trial

Abstract: levels declined across all groups. Among children receiving antibiotics, microbiota changes were notable only in the probiotic groups. However, no significant differences were observed in diarrhea duration or clinical symptoms between groups. These results suggest that probiotic supplementation can enhance gut microbial recovery during pediatric diarrhea and antibiotic exposure, although the added clinical benefits beyond standard care remain limited.

Source: iScience

DOI: 10.1016/j.isci.2025.113981

Authors: Shaojie Liang, Liujing Huang, Kai Ma, Runxin Wang, Feng Ji, Mingjie Shi, Mingxing Piao, Zhansui Liang, Runmin Guo, Riling Chen, Cheng Chen, Liwei Xie

Institutions: Guangdong Medical College, Foshan Maternity and Child Health Care Hospital, Guangdong Academy of Sciences, Zhejiang Chinese Medical University, Fuyao University of Science and Technology

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Children's Hospital of Philadelphia, National Natural Science Foundation of China, Guangdong Academy of Sciences

Awards: G2435367838, G5945440780

OpenAlex ID: W4416543444

FWCI: 0.879

Cites: 26

Cited by: 2

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