Ruminal microbial dysbiosis induces mastitis in dairy goats by activating oxidative stress and ferritinophagy-ferroptosis
Year: 2025
Type: article
Abstract: experiments showed that LPS dose-dependently triggered oxidative stress and ferritinophagy-ferroptosis in mouse mammary epithelial cells (MMECs). Collectively, HC diet-induced ruminal dysbiosis elevates systemic and mammary LPS levels, reduces antioxidant capacity, and activates oxidative stress and ferritinophagy-ferroptosis, ultimately leading to mastitis.
Source: iScience
Authors: Yuhong He, Wei Zhang, Can Zhang, Nier Su, Zeming Zhou, Chong Peng, Chongshan Yuan, Yunhe Fu, Xiaoyu Hu, Yue Zhang
Language: English
Subfield: Agronomy and Crop Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,240
Award: G2162180495
OpenAlex ID: W4416543765