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Identification of PGRMC1 as a regulator of the TLR3–TICAM1–IFNβ1 signaling axis in RAW264.7 macrophages

Year: 2025

Type: article

Abstract: expression. To the best of our knowledge, this is the first study to demonstrate that PGRMC1 contributes to regulating IFNβ1 production in response to TLR3 stimulation in RAW264.7 cells.

Source: Biochemistry and Biophysics Reports

DOI: 10.1016/j.bbrep.2025.102379

Authors: Hiroya Ohta, Kiyoshi Takahashi, Kayoko Takeda

Institution: Hokkaido University of Science

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,700

Funder: Hokkaido University

OpenAlex ID: W4416574389

FWCI:

Cites: 28

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