Work

Mechanistic Insights into the Allosteric Regulation of P53 Y220C by Small-Molecule Stabilizers

Year: 2025

Type: article

Source: Journal of Chemical Information and Modeling

DOI: 10.1021/acs.jcim.5c02062

Authors: Yiming Wen, Buying Niu, Jingyi Meng, Danye Chen, Xutong Li, Suilin Zhang, Hans Ågren, Mingyue Zheng, Dan Teng

Institutions: ShanghaiTech University, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research, Nanjing University of Chinese Medicine, University of Cambridge, Uppsala University

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, China Postdoctoral Science Foundation, Science and Technology Commission of Shanghai Municipality, Shanghai University of Traditional Chinese Medicine, National Key Research and Development Program of China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Awards: G1101904468, G1618279006, G2249194400, G3088239015, G3103939034, G4913652416, G5528081863, G5879120684, G792269649, G8039529882

OpenAlex ID: W4416583914

FWCI: 0.761

Cites: 46

Cited by: 3

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