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Reply to “Investigating a role for NSAIDs in the pathophysiology of vaccine-associated myocarditis”

Year: 2025

Type: letter

Abstract: Hoption Cann proposes that nonsteroidal anti-inflammatory drugs (NSAID)s could play an important role in the pathophysiology of vaccine-associated myocarditis and could also have a synergistic effect with COVID-19 vaccines, because NSAIDs are administered often as antipyretic medications. At this stage no hypothesis should be rejected a priori; however, we need to maintain rigor in the scientific evaluations so to advance research primarily towards the most plausible mechanisms.

Source: npj Vaccines

DOI: 10.1038/s41541-025-01285-9

Authors: Alessandra Buoninfante, Marco Cavaleri

Institution: European Medicines Agency

Language: English

Topic: Viral Infections and Immunology Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,890