Work

Hemorrhagic giant intra-abdominal desmoid tumor in twin pregnancy: a case report and literature review

Year: 2025

Type: article

Abstract: Background: Desmoid tumors (DTs) are rare, non-metastatic fibroblastic neoplasms known for their local invasiveness and slow growth. Their occurrence during pregnancy is rare, presenting unique diagnostic and therapeutic challenges, especially when complications like hemorrhage develop. Spontaneous hemorrhage in intra-abdominal DTs is an exceptionally rare complication. Case presentation: We report a 31-year-old woman, 32 + 4 weeks into a twin pregnancy, with a history of successful IVF-ET and routine prenatal care, who presented with acute left abdominal pain and signs of hemorrhagic shock. A computed tomography (CT) scan revealed a giant intra-abdominal mass (23.6×15.6×17.3 cm) with active bleeding. An emergency cesarean section and tumor resection were performed, which revealed a desmoid tumor (DT) invading the pancreas and transverse colon. Postoperative recovery was uneventful, and the patient was discharged in stable condition. Conclusion: This case underscores the importance of early multidisciplinary intervention in managing rare pregnancy-associated desmoid tumors (DT) complicated by hemorrhage. It emphasizes the necessity of heightened clinical suspicion in pregnant women presenting with acute abdominal pain.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1575315

Authors: Shizhao Wang, Zeqing Du, Lining Huang, Xiao Liu

Institutions: Second Hospital of Hebei Medical University, Hebei Medical University

Language: English

Topic: Soft tissue tumor case studies

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801