Differences in left ventricular functional properties in healthy adults with greater end-diastolic versus end-systolic aortic valve annular area—detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study
Year: 2025
Type: article
Abstract: Background: According to the literature, in one-third of the cases, the aortic valve annulus (AVA) is greater in end-diastole than in end-systole under certain conditions. Therefore, the purpose of the present study was to assess potential differences in left ventricular (LV) functional properties observed in healthy individuals, based on whether the end-diastolic or end-systolic AVA area was larger. Methods: ], who underwent two-dimensional (2D) Doppler echocardiography together with three-dimensional speckle-tracking echocardiography (3DSTE). Three subgroups were created: one with greater end-systolic AVA (n=70), one with equal end-systolic and end-diastolic AVA areas (n=8), and one with a greater end-diastolic AVA (n=34). Results: -20.9%±4.4%, P<0.05) compared with those with a greater end-systolic AVA area. Additionally, basal LV rotation proved to be significantly lower in subjects with normally directed LV rotational mechanics with greater end-diastolic AVA area compared with those with a greater end-systolic AVA area. Conclusions: Although most of healthy adults have a greater end-systolic than end-diastolic AVA area, 30% of cases show a greater end-diastolic AVA area. Healthy subjects with a greater end-diastolic AVA area demonstrated reduced basal radial and longitudinal LV strains, as well as lower basal LV rotation, compared with those with a greater end-systolic AVA area.
Authors: Attila Nemes, Nóra Ambrus, Csaba Lengyel
Institution: University of Szeged
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416613429