Work

CEBPB emerges as a key regulatory factor in human cancers through diverse molecular mechanisms and clinical implications

Year: 2025

Type: article

Abstract: CCAAT/enhancer-binding protein beta (CEBPB) is a critical transcription factor for cellular differentiation, inflammation, and metabolism. Recent studies have highlighted its dual role in tumorigenesis, functioning as both an oncogenic driver and tumor suppressor across diverse malignancies. This review synthesizes advances in understanding CEBPB's contributions to tumorigenesis, tumor progression, immune evasion, and therapy resistance, emphasizing its potential as a cancer-specific molecular biomarker in cancer diagnosis, prognosis and treatment.

Source: Discover Oncology

DOI: 10.1007/s12672-025-04122-6

Authors: Anbang He, Cunjin Wu, Dan Xia, Yi Zhu

Institutions: First Affiliated Hospital Zhejiang University, Zhejiang University

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,690