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Figure S7 from MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

Year: 2025

Type: other

Abstract: Supplemental Fig.S7. The TYK2 inhibitor, WU-76, reduces activation of STAT3 while stimulating activation of ERK1/2 in MPNST cells.

DOI: 10.1158/1078-0432.30706976

Authors: Dana C. Borcherding, Neha V. Amin, Kevin He, Xiaochun Zhang, Yang Lyu, Carina Dehner, Himanshi Bhatia, Angad Gothra, Layla Daud, Peter Ruminski, Christine A. Pratilas, Kai Pollard, Taylor Sundby, Brigitte C. Widemann, Angela C. Hirbe

Language: English

Topic: Neurofibromatosis and Schwannoma Cases

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4416628783

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