Supplementary Figure S16 from Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts
Year: 2025
Type: supplementary-materials
Abstract: EMK and IMP signature validation on HSPC sorted populations. Differential gene expression analysis across MDSRS+ with EMK profile, MDSRS- with IMP profile and NBM (3 cases each) according to Lin marker expression. Differential expressed genes (row) between EMK and IMP groups were selected. Each row represents a gene, and each column represents a sample. Design comparison (case) and sorted population (condition) are shown as covariates.
Authors: Gabriele Todisco, Maria Creignou, Elsa Bernard, Ann-Charlotte Björklund, Pedro Luis Moura, Bianca Tesi, Teresa Mortera-Blanco, Birgitta Sander, Monika Jansson, Gunilla Walldin, Indira Barbosa, Susanne E. Reinsbach, Isabel Juliana Hofman, Christer Nilsson, Tetsuichi Yoshizato, Marios Dimitriou, David Chang, Svannildur Olafsdottir, Sigita Venckute Larsson, Magnus Tobiasson, Luca Malcovati, Petter Woll, Sten Eirik W. Jacobsen, Elli Papaemmanuil, Eva Hellström-Lindberg
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4416629438