Work

CDK12 Deficiency Induces BRD4S to Promote Cancer Metastasis by Enhancing Phase Separation and Chromatin Engagement

Year: 2025

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-25-1761

Authors: Hao Li, Jindan Luo, Huaiyuan Liang, Yanfeng Bai, Jiandong Liu, Ting Wei, Liguo Wang, Hongshan Guo, Dan Xia, Haojie Huang, Rui Sun

Institutions: Mayo Clinic, First Affiliated Hospital Zhejiang University, Zhejiang University, Second Xiangya Hospital of Central South University, Qingdao University, Affiliated Hospital of Qingdao University

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Mayo Clinic, National Natural Science Foundation of China, Zhejiang University, Natural Science Foundation of Zhejiang Province, Science and Technology Program of Zhejiang Province, Key Research and Development Program of Zhejiang Province

Awards: G1440609827, G1930711166, G2951985152, G3748276720, 单细胞测序揭示乳腺导管原位癌的表观遗传调控异常, G7429214771

OpenAlex ID: W4416659347

FWCI: 0.254

Cites: 51

Cited by: 1

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