Work

Coronary artery calcification in type 1 diabetes after 10-year ketogenic diet

Year: 2025

Type: article

Abstract: In males with type 1 diabetes (T1D), 30-70% have a coronary artery calcification (CAC) score >1 in their thirties. The data in this case report indicate zero detectable CAC in a 30-39-yr-old male with T1D who followed a ketogenic diet for 10 years despite having an elevated low-density lipoprotein and no lipid-lowering medication. This suggests an absence of atherosclerotic plaque formation, despite concerns about the long-term cardiovascular consequences of a ketogenic diet.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00893.2025

Authors: Andrew P. Koutnik, Belinda S. Lennerz, Larry C. Deeb, Joseph C. Watso

Institutions: Florida State University, Florida Institute for Human and Machine Cognition, Boston Children's Hospital, Harvard University

Language: English

Topic: Diet and metabolism studies

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Silicon Valley Community Foundation, American Heart Association, National Heart, Lung, and Blood Institute, Congressionally Directed Medical Research Programs