Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Halo-borylsilylcarbanion reagents can be added, with complete stereofacial control, to chiral N - tert -butanesulfinyl imines, featuring an asymmetric C–C bond, followed by concomitant intramolecular asymmetric C–N bond formation. There is exclusive access to α,α-B,Si-disubstituted aziridine units containing up to four contiguous stereocenters in a single operation. In addition, complete stereochemical discrimination has been observed in N - tert -butanesulfinyl alkyl aldimines. Post-transformation of B,Si-disubstituted aziridine generates multichiral aziridine scaffolds.
Source: JACS Au
Institutions: Universitat Rovira i Virgili, Sanofi (Germany)
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,500
OpenAlex ID: W4416673294