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Successful Treatment of Escherichia coli ‐Related Spondylitis With an Extended Meropenem Infusion Time for a 72‐Year‐Old Woman: A Case Report

Year: 2025

Type: article

Abstract: ABSTRACT Escherichia coli ( E. coli ) causes spinal infections relatively rarely and is often closely associated with parenteral infections. E. coli spondylitis can cause fever and local pain and, in severe cases, can lead to bone destruction, abscess formation, and even the risk of high paraplegia. Therefore, timely and precise diagnosis and effective treatment are crucial. We report successful conservative management of E. coli spondylitis in a 72‐year‐old female using metagenomic sequencing‐guided prolonged meropenem infusion. Extending the infusion time of meropenem achieved clinical resolution without surgery, demonstrating this strategy's efficacy for carbapenem‐sensitive spinal infections.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71531

Authors: Wang Hongbin, Xu Jing, Wang Xianwei, Guo Hui, Fan Xutao

Institutions: Jining Medical University, Affiliated Hospital of Jining Medical University

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820