Work

Age-dependent immune responses and resident cell dynamics in young mice following pneumonia

Year: 2025

Type: article

Abstract: on the lung. This study highlighted how early-life immune ontogeny impacts disease susceptibility, opening avenues for future research to identify therapeutic targets to enhance resistance to respiratory infections for the most vulnerable populations.

Source: iScience

DOI: 10.1016/j.isci.2025.114219

Authors: Sylvia N. Michki, Javier V. Perez, Dharma A. Varapula, Aaron J. Thomas, Tiffaney L. Vincent, Benjamin D. Singer, Jarod A. Zepp, Sharon A. McGrath-Morrow

Institutions: Children's Hospital of Philadelphia, Northwestern University

Language: English

Topic: Immune responses and vaccinations

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Foundation for the National Institutes of Health, National Institutes of Health, National Institute of General Medical Sciences

Awards: Epigenetic modifiers of regulatory T cell function following viral pneumonia, Disordered Proteostasis as a Driver of Disease in the Aging Lung, G9000299527, Mechanisms of regulatory T cell-mediated recovery from severe viral pneumonia, Lung repair mechanisms mediated by the immune-fibroblast interface, Mechanisms of Recovery from Viral Pneumonia

OpenAlex ID: W4416684170

FWCI:

Cites: 70

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