Work

Ruthenium‐ and Rhodium‐Catalyzed CH Bond Allylation of 2‐Aryl‐3 H ‐Indoles With Vinylcyclopropanes

Year: 2025

Type: article

Abstract: The Ru(II)‐ and Rh(III)‐catalyzed CH/CC bond activation and subsequent allylation of 2‐aryl‐3 H ‐indoles with vinylcyclopropanes (VCPs), 2‐vinyl‐ethylene oxide, and 2‐vinylaziridine are reported, enabling the expedient preparation of a wide spectrum for indole derivatives. This transformation proceeds using a cascade sequence involving CH bond activation, CC bond cleavage of VCPs, and 1,2‐migratory alkene insertion.

Source: European Journal of Organic Chemistry

DOI: 10.1002/ejoc.202500920

Authors: Ze Li, Jianhui Wang

Institutions: Tianjin University, Collaborative Innovation Center of Chemical Science and Engineering Tianjin

Language: English

Topic: Catalytic C–H Functionalization Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funder: National Natural Science Foundation of China

Awards: 高效Z-选择性钌卡宾烯烃复分解催化剂的合成与催化研究, 含类卡宾配体的钌烯烃复分解催化剂合成与催化研究