Work

Total syntheses of ent -aogacillin A and aogacillin B

Year: 2025

Type: article

Abstract: The first asymmetric total syntheses of aogacillin B and ent -aogacillin A and were reported in 7 steps, featuring a one-pot aldol/lactonization reaction.

Source: Chemical Science

DOI: 10.1039/d5sc04554a

Authors: Huixing Gu, Ziyi Li, Xinwei Zhang, Ruocheng Sang, Zhendong Li, Jinyi Ren, Xiaojing Chen, Boya Ma, Wenhao Qiu, Zebin Yang, Xiaoyan Li, Rongbiao Tong, Wei Zhang

Institutions: Hebei Normal University, Hong Kong University of Science and Technology

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Hebei Provincial Department of Human Resources and Social Security, Research Grants Council, University Grants Committee, Hebei Normal University, Natural Science Foundation of Hebei Province

Awards: G3028491691, Development of Aza-Achmatowicz Rearrangement-based Approach for Construction of 2-ABN and Total Synthesis of Akuammiline Alkaloids, G4404437268, Chemical Synthesis of Broad-spectrum Anticancer Withaferin A and Related Withanolides, G6300580941, G6478208675, Total Synthesis of Spirotetronate Polyketide Spirohexenolides A and B

OpenAlex ID: W4416692039

FWCI:

Cites: 40

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