Work

Clog-free all-aqueous microfluidic fabrication of hydrogel microfibers governed by a universal scaling law

Year: 2025

Type: article

Abstract: . Finally, we demonstrate encapsulation of pancreatic β-cells, which retain glucose-responsive insulin secretion comparable to that of unencapsulated cells. This work establishes the physical basis of all-aqueous microfiber fabrication and provides a robust, scalable, and cytocompatible approach for cell encapsulation.

Source: Lab on a Chip

DOI: 10.1039/d5lc01007a

Authors: Jinchang Zhu, Yi He, Jing Wang, Isabella Powell, Pu Zhang, Anthony Ouertani, Yong Wang, Li-Heng Cai

Institution: University of Virginia

Language: English

Topic: Microfluidic and Capillary Electrophoresis Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Funders: Virginia Innovation Partnership Corporation, National Institutes of Health, National Institute of General Medical Sciences

Awards: G2943142456, Constructing 3D voxelated tissues with molecular architecture encoded modular biomaterials to understand and control stem cell function, G50695551

OpenAlex ID: W4416697453

FWCI:

Cites: 31

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