Work

Potent and selective G protein-coupled receptor kinase 5 inhibitors: Design, synthesis, evaluation, and X-ray structural studies

Year: 2025

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2025.118393

Authors: Arun K. Ghosh, Rajesh Manda, Ranjith Kumar Gadi, Yueyi Chen, Natalie M. Galvan, John J.G. Tesmer

Institution: Purdue University West Lafayette

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Walther Cancer Foundation, Purdue University, National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: Cancer Center Support Grant, Structure, function, and inhibition of G protein-coupled receptor kinases

OpenAlex ID: W4416702215

FWCI: 0.298

Cites: 36

Cited by: 1

Related to: 10