Metabolic associated steatotic liver disease in Qatar: Analysis of dietary patterns and nutrient intake
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common and increasingly prevalent condition in the Middle East, but its determinants in the region are underexplored. Diet and lifestyle are known to significantly influence MASLD progression. AIM To assess energy and nutrient intake among MASLD patients living in Qatar and evaluate their dietary patterns. METHODS Using a cross-sectional design, 94 Arab patients with MASLD, aged ≥ 18 years, living in Qatar were studied. MASLD was diagnosed using ultrasonography, fibro scan, or elastography. Sociodemographic information was collected using a self-administered questionnaire. Dietary intake was assessed through three 24-hour recalls and a qualitative food frequency questionnaire. Energy, macro-, and micronutrient intake were analyzed using Elizabeth Stewart Hands and Associates Food Processor® Nutrition Analysis software. Statistical analyses, including factor loadings were performed using STATA 18. RESULTS Compared to recommended dietary allowance, MASLD patients had high intakes of fat, saturated fat, and cholesterol. They also showed reduced intakes of vitamin K in men, and vitamins E and A (retinol), calcium and magnesium in both genders, while selenium and sodium intakes were higher than recommendations. Three dietary patterns were identified: The ‘Traditional Qatari food’ pattern, the ‘Prudent’ pattern, and the ‘Fast-food’ pattern. However, no significant associations were found between these dietary patterns and body mass index or low-density lipoprotein, using adjusted regression models. CONCLUSION Findings warrant replication in longitudinal studies and call for dietary interventions to reduce energy density and enhance overall diet quality, including micronutrient intake, for MASLD prevention and management in the region.
Source: World Journal of Hepatology
Institutions: Qatar University, Hamad Medical Corporation
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funders: Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, AstraZeneca, American Association for the Study of Liver Diseases, Gilead Sciences, Celgene, CSL Behring, NGM Biopharmaceuticals, Coherus Biosciences, Eisai, Novo Nordisk, Astellas Pharma, Shionogi, European Association for the Study of the Liver, Swedish Orphan Biovitrum, Genentech, Allergan
OpenAlex ID: W4416714079