Work

Antenatal Corticosteroids for Bronchopulmonary Dysplasia—Mediation Analysis and Causal Reasoning

Year: 2025

Type: article

Abstract: Antenatal corticosteroids (ACS), administered to pregnant women at risk of preterm birth, represent one of the most successful stories in modern medicine.They have also deservedly inspired the logo of the Cochrane Collaboration, which illustrates the forest plot of a systematic review on this topic.While every doctor knows the importance of ACS, it is nonetheless useful to remind that preterm neonates whose mothers receive ACS have a significantly lower risk not only of death but also of respiratory distress syndrome (RDS) and mechanical ventilation, intracranial hemorrhage, necrotizing enterocolitis, and other conditions, compared with neonates whose mothers do not receive ACS.

Source: JAMA Network Open

DOI: 10.1001/jamanetworkopen.2025.45617

Authors: Luigi Gagliardi, Franca Rusconi

Institution: Azienda USL Toscana Nord Ovest

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000