Supplementary Figure 1. from Association of Urinary Biomarkers of Smoking-Related Toxicants with Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study
Year: 2025
Type: supplementary-materials
Abstract: Distribution plot of pack-years and urinary biomarkers of smoking-related toxicants both without and with transformation for the Multiethnic Cohort (MEC) subcohort of current smokers at time of urine collection. Figure A. Distribution plot of pack-years without transformation; Figure B. Distribution plot of pack-years divided by the overall population standard deviation (with transformation); Figure C. Distribution plot of total nicotine equivalents (TNE) without transformation; Figure D. Distribution plot of TNE with transformation; Figure E. Distribution plot of the ratio of total trans 3’-hydroxycotinine (3-HCOT)/cotinine (Total 3-HCOT/cotinine) without transformation; Figure F. Distribution plot of Total 3-HCOT/cotinine with transformation; Figure H. Distribution plot of 4-(methylnitrosamino)-1-3-pyridyl)-1-butanol (Total NNAL) without transformation; Figure I. Distribution plot of Total NNAL with transformation; Figure J. Distribution plot of S-phenylmercapturicacid (SPMA) without transformation; Figure J. Distribution plot of SPMA with transformation; Figure K. Distribution plot of 3-hydroxypropyl mercapturic acid (3-HPMA) without transformation; Figure L. Distribution plot of 3-HPMA with transformation; Figure M. Distribution plot of phenanthrene tetraol(PheT) without transformation; Figure N. Distribution plot of PheTwith transformation; Figure O. Distribution plot of 3-hydroxyphenanthrene (PheOH) without transformation; Figure P. Distribution plot of PheOH with transformation; Figure Q. Distribution plot of PheT/PheOH (a proposed biomarker of metabolic activiation of polycyclic aromatic hydrocarbons) without transformation; Figure R. Distribution plot of PheT/PheOH with transformation; Figure S. Distribution plot of cadmium (Cd) without transformation; Figure T. Distribution plot of Cd with transformation; Plot U. Distribution plot of (Z)-7-[1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid (8-iso-PGF2α) without transformation; Figure V. Distribution plot of 8-iso-PGF2α with transformation.
Authors: Shannon S. Cigan, Sharon E. Murphy, Daniel O. Stram, Stephen S. Hecht, Loïc Le Marchand, Irina Stepanov, Sungshim L. Park
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4416719528
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