Work

Efectos diferenciales de la estimulación cognitiva computarizada y las actividades de ocio estimulantes sobre el estado de ánimo y la cognición global en adultos con deterioro cognitivo subjetivo y leve: Ensayo controlado aleatorizado

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: BACKGROUND: Mild Cognitive Impairment (MCI) involves both subjective and objective cognitive decline with relatively preserved daily functioning, whereas Subjective Cognitive Impairment (SCI) refers to perceived decline without measurable deficits. This study aimed to compare the effects of a personalized computerized cognitive stimulation (CS) program (IG1) and a stimulating leisure activities program (IG2) in adults with MCI and SCI. METHODS: A single-blind randomized controlled trial was conducted in primary care with participants aged =50 years with SCI or MCI. Participants were randomized to IG1, IG2), or a control group (CG). IG1 completed personalized computerized CS for 30 minutes/day, 5 days/week, for 8 weeks. IG2 engaged in 2-5 stimulating leisure activities per week for the same period. The primary outcome was global cognition; secondary outcomes included memory, verbal fluency, daily functioning, and mood. RESULTS: Fifty-nine participants were enrolled in the study, 44 with SCI and 15 with MCI. Compared to CG, IG1 showed greater reductions in anxiety post-intervention (2.07; 95%CI: 0.93-3.22 vs. 4.34; 95%CI: 3.22-5.46) and lower depressive symptoms at 6-month follow-up (3.41; 95%CI: 2.05-4.77 vs. 5.62; 95%CI: 4.26-6.97). IG2 participants demonstrated improved global cognition post-intervention (29.2; 95%CI: 27.625-30.776) and at 6 months (28.78; 95%CI: 27.16-30.42) relative to CG (30.626; 95%CI: 28.99-32.27). CONCLUSION: Personalized computerized CS reduces anxiety and depression symptoms, while stimulating leisure activities enhances global cognition in community-dwelling adults with SCI and MCI, suggesting complementary benefits of both interventions.

Source: Anales del Sistema Sanitario de Navarra

DOI: 10.23938/assn.1136

Authors: Isabel Gómez-Soria, Juan Nicolás Cuenca-Zaldivar, Bárbara Oliván-Blázquez, Alejandra Aguilar Latorre, Rosa Mª Magallón-Botaya, Estela Calatayud

Institutions: Universidad de Zaragoza, Instituto de Investigación Sanitaria Aragón, Fundación para la Investigación e Innovación Biosanitaria de Atención Primaria

Language: English

Topic: Dementia and Cognitive Impairment Research

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Gobierno de Aragón