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Enzymatic Anti-Baldwin Ring-Closure Cascade for Fused Bicyclic Ether Formation

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Year: 2025
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.5c17188
Authors: Michio Sato, Yui Ito, Tomomi Kagoura, Sakurako Sakano, Yuta Tsunematsu, Jinkai Cheng, Pauline Bianchi, K. N. Houk, Kenji Watanabe
Institutions: Shizuoka University, University of Shizuoka, Nagoya University, University of California, Los Angeles
Language: English

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences

Open Access status: closed

Funders: Belgian American Educational Foundation, Uehara Memorial Foundation, Japan Agency for Medical Research and Development, Directorate for Biological Sciences, Japan Society for the Promotion of Science
Awards: G1468744672, G1756637430, Identification of target molecules based on self-resistance gene-directed genome mining, Understanding a mechanism of an onset of colorectal cancer by colibactin and finding compounds inhibiting colibactin biosynthetic enzymes, G4483207381, G5611369256, Toward engineered biosynthesis of drugs in human cells, Understanding a mechanism of an onset of colorectal cancer by colibactin and finding a inhibitor to the biosynthetic enzymes, G8665334841
OpenAlex ID: W4416724398
FWCI: 1.449
Cites: 37
Cited by: 3
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