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Genetic evidence supports primary biliary cholangitis as a risk factor for lacunar stroke

Year: 2025

Type: article

Abstract: = 0.0026). Sensitivity analyses indicated no significant pleiotropy and confirmed result robustness. This genetic evidence suggests PBC is a causal risk factor for lacunar stroke, warranting further investigation and targeted prevention.

Source: iScience

DOI: 10.1016/j.isci.2025.114240

Authors: Mengmeng Wang, Nan Zhang, Ling Zhang, Ning Zhang, Haichu Yu

Institutions: Affiliated Hospital of Qingdao University, Third Affiliated Hospital of Sun Yat-sen University, Heze Municipal Hospital, Qingdao University

Language: English

Topic: Liver Diseases and Immunity

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: National Natural Science Foundation of China, Qingdao Municipal Science and Technology Bureau

Awards: G2185800563, G4083450794

OpenAlex ID: W4416733069

FWCI:

Cites: 48

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