Work

Design, Synthesis, and Biological Evaluation of the Novel Neutrophil Elastase Inhibitor CHF-6333 for the Inhaled Treatment of Bronchiectasis

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02638

Authors: Elisabetta Armani, Andrea Rizzi, Daniela Miglietta, Irene Bassanetti, Francesco Amadei, Giandomenico Brogin, Carmelida Capaldi, Fabio Rancati, Chiara Carnini, Sergio Xanxo Fernandez, Maurizio Civelli, Paola Puccini, Marta Bellini, Andrew Jennings, Robert A. Heald, Lilian Alcaraz, Jonathan M. Sutton, Harry Finch, Mary Fitzgerald, Craig Fox, Gino Villetti

Institutions: Chiesi (Italy), Charles River Laboratories (United Kingdom), Charles River Laboratories (United States), Pulmagen Therapeutics (United Kingdom)

Language: English

Topic: Inhalation and Respiratory Drug Delivery

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4416742883

FWCI: 0.595

Cites: 33

Cited by: 1

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