Work

Zwitterionic MRI contrast agents with enhanced relaxivity, stability and reduced renal retention

Year: 2025

Type: article

Abstract: Zwitterionic PCTA derivatives form highly stable Gd( iii ) complexes with high relaxivity and favorable biodistribution in vivo . They are promising candidates for the development of next-generation contrast agents for magnetic resonance imaging (MRI).

Source: Journal of Materials Chemistry B

DOI: 10.1039/d5tb02336j

Authors: Lennart F. V. Spickschen, Verena R. Schulze, Michael G. Kaul, Darius Ludolfs, Marie Oest, Daniel L. J. Thorek, Neus Feliu, Markus Fischer, John V. Frangioni, Wolfgang Maison

Institutions: Universität Hamburg, Fraunhofer Institute for Applied Polymer Research, University Medical Center Hamburg-Eppendorf, Washington University in St. Louis, Curadel (United States)

Language: English

Topic: Lanthanide and Transition Metal Complexes

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4416746410

FWCI: 0.623

Cites: 45

Cited by: 3

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