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Accidental Daily Dosing: Severe Methotrexate Toxicity in a Patient with Rheumatoid Arthritis

Year: 2025

Type: article

Abstract: This case highlights a crucial complication of oral methotrexate therapy: toxicity due to dosing errors. A patient’s daily dosing regimen, instead of the intended weekly schedule, led to a significantly excessive cumulative dose of methotrexate over a short period, resulting in severe hematologic and mucosal toxicity. This underscores the importance of clear patient education and vigilant prescription practices to prevent such errors.

Source: Advances in Clinical Medical Research and Healthcare Delivery

DOI: 10.53785/2769-2779.1331

Authors: Sidra Memon, Kavitha Vemuri, Syed Uzair Mahmood, Darshit Patel

Institution: The University of Texas Health Science Center at Houston

Language: English

Topic: Patient Safety and Medication Errors

Subfield: Emergency Medical Services

Field: Health Professions

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4416755276

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