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Xanthogranulomatous prostatitis: A case report

Year: 2025

Type: article

Abstract: Xanthogranulomatous Prostatitis (XGP) is a rare benign inflammatory condition of the prostate. Patients typically present with lower urinary tract symptoms or elevated serum prostate-specific antigen (PSA) levels. Differentiating XGP from prostate cancer (PCa) based solely on multiparametric MRI (mpMRI) findings remains challenging, as histopathological examination is the gold standard for definitive diagnosis. This case report describes a 57-year-old man diagnosed with XGP. Symptomatic remission was achieved following a 4-week course of antibiotic therapy combined with an alpha-blocker. • Diagnostic Challenges: This case highlights the limitations of pre-operative imaging and serum markers in distinguishing XGP from malignancy, underscoring the critical role of histopathological confirmation. • Conservative Management Success: It demonstrates a successful outcome with a 4-week regimen of levofloxacin and tamsulosin, offering a valuable reference for the non-surgical management of selected XGP cases.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103293

Authors: Jun Yang, Yuan-Yuan Zhu, Shao-Jun Li

Institution: Gansu Provincial Maternal and Child Health Hospital

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160