Work

Engineering Imine Reductase for the Synthesis of Pharmaceutically Relevant 1-Aminomethylbenzocycloalkanes via Dynamic Kinetic Resolution–Asymmetric Reductive Amination

Year: 2025

Type: article

Source: Organic Letters

DOI: 10.1021/acs.orglett.5c04386

Authors: Xiaoshi Lv, Zefei Xu, Xiangtao Liu, Jinhui Feng, Hongkai Zhang, Peiyuan Yao, Qiaqing Wu, Dunming Zhu

Institutions: Chinese Academy of Sciences, Nankai University, Tianjin Institute of Industrial Biotechnology, State Key Laboratory of Medicinal Chemical Biology

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funder: National Natural Science Foundation of China

Awards: G8641102569, G872476815

OpenAlex ID: W4416767792

FWCI: 0.261

Cites: 27

Cited by: 1

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