Work

Does the Use of a Bioceramic Sealer Reduce Postoperative Pain Compared With an Epoxy Resin‐Based Sealer After Primary Root Canal Treatment and Retreatment?—An Umbrella Review

Year: 2025

Type: article

Abstract: BACKGROUND: Postoperative pain (POP) is a frequent occurrence after root canal treatment (RCT). There is conflicting evidence regarding the prevalence of POP after root canal filling with a bioceramic sealer in comparison with an epoxy resin-based sealer. OBJECTIVE: To ascertain whether the use of a bioceramic sealer reduces POP in comparison with an epoxy-resin-based sealer in combination with gutta percha following primary RCT and retreatment. METHODS: A literature search was carried out in electronic databases from inception to 20 January 2025. Systematic reviews (SRs) that evaluated the POP using bioceramic sealers when compared with epoxy resin-based sealers were included. The quality of the reviews was evaluated employing the AMSTAR 2 tool. The overall confidence in the findings of the review was categorised as critically low, low, moderate or high. RESULTS: In total, 13 SRs were included. The POP experienced when bioceramic sealers were used in combination with gutta percha was similar to that of epoxy resin-based sealers. All the SRs adequately addressed Item 1 ('Did the research questions and inclusion criteria for the review include the components of PICO?'). Only one SR adequately addressed Item 3 ('Did the review authors explain their selection of the study designs for inclusion in the review?') and Item 10 ('Did the review authors report on the sources of funding for the studies included in the review?'). The overall confidence in the findings of ten, two and one SR(s) was classified as 'critically low', 'low' and 'high', respectively. CONCLUSION: Based on current evidence, it can be concluded that root canal filling with a bioceramic sealer demonstrated POP that was comparable to that of epoxy resin-based sealers following primary RCT and retreatment. As per the recommendations in this umbrella review regarding the methodological quality of existing SRs, high-quality SRs are necessary in the future. TRIAL REGISTRATION: PROSPERO database: CRD42024616520.

Source: International Endodontic Journal

DOI: 10.1111/iej.70073