Work

Addison’s disease in patients with autoimmune primary ovarian insufficiency: a concise guide for gynecologists and obstetricians

Year: 2025

Type: article

Abstract: Addison's disease (AD) is a rare condition, but its prevalence in Europe has been steadily rising. Its initial presentation might be a life-threatening event termed adrenal crisis (AC), which is particularly likely to happen during situations of increased biological stress, such as septic illness, general anesthesia, surgery, or trauma.Addison's disease can appear as an isolated clinical entity or together with other autoimmune conditions, such as autoimmune thyroiditis, pernicious anemia, or autoimmune primary ovarian insufficiency (POI). In this review, we underline the relationship between AD and POI with a special regard for patients with POI who might develop AD. Due to the nonspecific symptoms of AD, patients often consult multiple specialists before receiving a proper diagnosis, which delays the recognition of AD Ordering basic screening tests might facilitate an early detection of AD and prevent possibly fatal complications of the disease.

Source: Ginekologia Polska

DOI: 10.5603/gpl.107606

Authors: Iga Tartas, Julia Neumann, Stanislaw Wardecki, Agata Berlinska, Anna Lewczuk-Myslicka, Renata Swiatkowska-Stodulska

Institutions: Gdańsk Medical University, University Clinical Centre

Language: English

Topic: Adrenal Hormones and Disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $431