Waldenström’s macroglobulinemia: The LYSA pragmatic guidelines
Year: 2025
Type: article
Abstract: Waldenström's macroglobulinemia (WM) is a rare, indolent B-cell lymphoma that predominantly affects older adults. In recent years, significant progress has been made in understanding its pathogenesis, identifying relevant biomarkers, and developing novel therapeutic approaches to complement traditional chemoimmunotherapy-collectively reshaping the management landscape of WM. In this article, we provide comprehensive, evidence-based recommendations for the diagnosis, molecular evaluation, and treatment of WM, including strategies for both frontline and relapsed disease. These guidelines are informed by the latest clinical research, expert consensus, and current practice standards, with the goal of equipping clinicians with a practical and effective framework for delivering optimal care to patients with WM.
Source: European Journal of Cancer
Authors: Damien Roos-Weil, Cécile Tomowiak, Stéphanie Poulain, Florence Nguyen-Khac, Florian Bouclet, Marine Armand, Thérèse Aurran, Eric Durot, David Ghez, Bénédicte Hivert, Kamel Laribi, Magali Le Garff Tavernier, Stéphane Lepretre, Lydia Montes, Amine Moslemi, Laurence Simon, Véronique Leblond, Pierre Morel, Olivier Tournilhac
Institutions: Inserm, Université Paris Cité, Sorbonne Université, Centre de Recherche des Cordeliers, Pitié-Salpêtrière Hospital, Centre Hospitalier Universitaire de Poitiers, Centre National de la Recherche Scientifique, Université de Lille, Centre Hospitalier Universitaire de Lille, Assistance Publique – Hôpitaux de Paris, Centre Henri Becquerel, Institut Paoli-Calmettes, Centre Hospitalier Universitaire de Reims, Institut Gustave Roussy, Groupe Hospitalier de l'Institut Catholique de Lille, Centre Hospitalier du Mans, Centre Hospitalier Universitaire Amiens-Picardie, Centre Hospitalier Sud Francilien, Centre Hospitalier Universitaire de Clermont-Ferrand
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,270
OpenAlex ID: W4416796050