Year: 2025
Type: article
Study design: Case Report
Abstract: Anti-glomerular basement membrane (GBM) disease is usually a monophasic condition. Relapses are uncommon and linked to triggers like smoking, inhalation of solvents, hair dye, or infections. We report a 43-year-old male with biopsy-proven anti-GBM disease who was initially treated with plasmapheresis, steroids, and cyclophosphamide. After 2 months, following the use of a new hair dye, he developed diffuse alveolar hemorrhage with increased anti-GBM antibody titers. He was managed with plasmapheresis, intravenous immunoglobulins, and rituximab. This case highlights the importance of avoiding triggers and supports the role of rituximab in relapsing disease.
Source: Indian Journal of Nephrology
Authors: Mahima Dhingra, S. Sobiya, Kulwant Singh, Deepak Kumar Panigrahi, Abhishek Singh, Dinesh Khullar
Institution: Max Super Speciality Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416811186