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Cure sometimes, treat often, comfort always: reflections on the feasibility and timing of trials in the palliative setting

Year: 2025

Type: article

Abstract: Cachexia, the EMPATICC trial, and the challenges of clinical trials in the palliative care setting. Cachexia is an important feature of both heart failure and cancer, with impact on mortality and morbidity. Hence, targeting cachexia likely has clinical value; however, optimal endpoint choice and trial conduct in this setting is poorly defined.

Source: European Heart Journal

DOI: 10.1093/eurheartj/ehaf900

Authors: Charlotte H Manisty, Ninian N Lang

Institutions: National Health Service, Barts Health NHS Trust, University College London, University of Glasgow

Language: English

Topic: Palliative Care and End-of-Life Issues

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Barts Health NHS Trust