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Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis

Year: 2025
Type: article
Abstract: KEY POINTS: Eosinophil peroxidase (EPX) correlates with local type 2 inflammation and may serve as a noninvasive biomarker of eosinophilic chronic rhinosinusitis. EPX declines after surgery and dupilumab, highlighting its potential to track treatment response. High baseline EPX predicts patients likely to achieve a clinically meaningful Sinonasal Outcome Test-22 change.
DOI: 10.1002/alr.70076
Authors: Jacquelyn K. Callander, Annabelle R. Charbit, Camryn Marshall, Kritika Khanna, Steven D. Pletcher, Jose G. Gurrola, Andrew H. Murr, Monica Tang, Andrew N. Goldberg, Patricia A. Loftus
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $4,100
OpenAlex ID: W4416816850
FWCI: 1.46
Cites: 9
Cited by: 2
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