Work

Hepatoid Carcinoma of the Ovary: Case Report, Clinical Management, and Insights From Literature Review

Year: 2025

Type: article

Abstract: Hepatoid carcinoma of the ovary (HCO) is an exceedingly rare epithelial ovarian malignancy demonstrating hepatocellular differentiation and marked serum AFP elevation. Due to its rarity, existing literature remains limited, and optimal management strategies remain undefined. Emerging evidence highlights the urgent need for improved recognition of HCO among clinicians and pathologists to enable early diagnosis and inform optimal treatment. In this study, we present a case of HCO from our institution and integrate this with a synthesis of recent advances in the field. This article aims to provide a comprehensive overview of HCO, with the goal of improving clinical awareness and guiding future research directions.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71496

Authors: Nan Zhang, Zhilan Liu, Dengfeng Cao, Weihua Lou

Institutions: Shanghai Jiao Tong University, Renji Hospital, Shanghai Key Laboratory of Gynecologic Oncology

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820