Severe Malaria and Mechanical Ventilation in Pregnancy: The Crucial Role of Fetal Doppler in Monitoring Fetal Well-Being
Year: 2025
Type: article
Study design: Case Report
Abstract: A 33-year-old multiparous woman with no relevant medical history, at 33 weeks of gestation, presented to the emergency department of a tertiary care hospital with a five-day history of fatigue, arthralgia, chills, and abdominal pain. The patient rapidly developed respiratory failure and was intubated and placed on mechanical ventilation. Continuous fetal monitoring, including Doppler velocimetry, was performed to assess fetal well-being during maternal respiratory support. Fetal Doppler evaluations demonstrated reassuring parameters during mechanical ventilation, with normal umbilical artery and middle cerebral artery flow patterns. No signs of fetal hypoxia or centralization were observed. A review of the literature identified fewer than a dozen case reports or series involving mechanical ventilation in pregnant patients, most commonly associated with severe pneumonia, acute respiratory distress syndrome, or trauma. Few studies addressed fetal monitoring strategies or outcomes related to Doppler indices during maternal ventilation. This case highlights the feasibility and importance of fetal Doppler surveillance in pregnant patients undergoing invasive mechanical ventilation. Despite limited data, current evidence suggests that individualized maternal ventilatory management, coupled with serial fetal assessment, can support favorable perinatal outcomes. Further studies are needed to define optimal respiratory parameters and standardized fetal monitoring protocols in this unique clinical scenario.
Source: Cureus
DOI: 10.7759/cureus.98109
Authors: Sandra Olaya, Sergio David Angulo, Jezid Miranda, Manuel Garay
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416823016