Work

Concurrent benign leiomyomas in heart, lung, and abdomen: a case report

Year: 2025

Type: article

Abstract: BACKGROUND: Benign metastasizing leiomyoma is a rare disease characterized by the spread of benign smooth muscle tumors, primarily affecting premenopausal women with a history of myomectomy or hysterectomy. The unclear pathogenesis complicates diagnosis. CASE PRESENTATION: We report a 50-year-old Iranian woman with concurrent masses involving the lung, heart, and uterus. While initially suspected to be malignant, pathological evaluation demonstrated a uterus mass with benign nature but metastatic behavior, confirming the benign metastasizing leiomyoma diagnosis with evaluation of the patient's condition post-surgery. The condition affected critical organs, specifically the heart and lungs. Sadly, the patient's health deteriorated after surgery, leading to her death. CONCLUSION: This case shows the rare potential of benign metastasizing leiomyoma to involve vital organs such as the heart and lungs. It highlights the need for vigilance and timely evaluation of new symptoms rather than routine multi-organ screening in all patients with uterine leiomyomas. Notably, we identified a rare subtype of this tumor that exhibits aggressive characteristics.

Source: Journal of Medical Case Reports

DOI: 10.1186/s13256-025-05717-x

Authors: Hale Afshar, Pegah Babaheidarian, Marziyeh Ghalamkari, Mahboubeh Pazoki, Shokoufeh Haj Sadeghi, Maedeh Olya

Institution: Iran University of Medical Sciences

Language: English

Topic: Uterine Myomas and Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,890