Year: 2025
Type: article
Study design: Systematic Review
Abstract: Dermoscopy has revolutionized dermatological diagnostics by enabling the visualization of subsurface skin structures.Among various dermoscopic features, rosettes have gained attention due to their distinctive appearance and diagnostic implications.1 Figure 1 illustrates the characteristic appear ance of rosettes, as seen in polarized light dermoscopy.This review summarizes existing literature on rosettes in dermatology, highlighting their broader clinical relevance across disease categories and comparing findings with earlier fragmented reports.While prior mentions of rosettes have appeared in case series and reviews focused on actinic keratoses, this review compiles evidence across neoplastic, inflammatory, infectious, and vascular conditions, offering a more comprehensive, structured overview.Recognizing the spectrum of conditions associated with rosettes is crucial for accurate diagnosis and management.The emergence of polarized dermoscopy has facilitated the detection of these structures, which remain invisible under nonpolarized light. 2 This review synthesizes existing literature on rosettes in dermatology, highlighting their clinical relevance and differential diagnosis. MethodologyA systematic literature search was conducted following the Preferred Reporting Items for Systematic Reviews and MetaAnalyses guidelines.3 The search was performed in December 2024 across MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Web of Science.Keywords used included "rosettes, " "dermoscopy, " "polarized light, " "cutaneous neoplasms, " and "inflammatory skin diseases." Studies published in English, reporting rosettes in various dermatological conditions, were included, while reviews, editorials, and nonEnglish articles were excluded.Both observational and casecontrol studies were considered.Reference lists of relevant studies were manually searched for additional articles.
Author: Sharang Gupta
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4416840275