Work

TFE3-rearranged renal cell car cinoma with massive calcification: Imaging-pathologic correlation

Year: 2025

Type: article

Abstract: Transcription Factor E3 (TFE3)-rearranged renal cell carcinoma (RCC) is rare. Radiologically, TFE3-rearranged RCC typically appears as a hyperattenuating mass with calcifications. Calcifications typically appear as small punctate or irregular coarse deposits, which are pathologically associated with granular and collagenous stromal degeneration. Here, we report a case of TFE3-rearranged RCC with extensive calcification in a young female, emphasizing imaging-pathologic correlation to enhance diagnostic accuracy. This case underscores the importance of recognizing atypical radiological features in rare RCC subtypes.

Source: Journal of Clinical Imaging Science

DOI: 10.25259/jcis_126_2025

Authors: Wenjuan Wang, Wenjuan Wang, Hao Ma, Wengang Wang, Wengang Wang, Dmytro Pylypenko

Institution: Weifang People's Hospital

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4416844246