The Mystery Plaque: Unraveling a Singular Perioral Granulomatous Enigma
Year: 2025
Type: article
Study design: Case Report
Abstract: ABSTRACT: A 34-year-old lactating woman presented with erythematous indurated plaques around the perioral region, extending to the nose and forehead, mimicking granulomatous dermatoses. Dermoscopy showed follicular plugging and dermal inflammation. Histopathology revealed epithelioid cell granulomas with giant cells and nerve infiltration, confirming borderline tuberculoid leprosy. The patient was treated with multidrug therapy and closely monitored for reactions. This case underscores the diagnostic challenge of Hansen's disease with atypical centrofacial presentation and emphasizes the importance of histopathological confirmation for timely treatment, particularly in vulnerable groups such as lactating mothers.
Source: Annals of African Medicine
Authors: Nishtha Mishra, Sarthak Bansal, Asharbh Raman, Gauri Sharma
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4416850786