Work

Detecting quality of life alterations in people living with HIV: Development and evaluation of the OCTAVE® self-questionnaire

Year: 2025

Type: article

Abstract: • We report on the findings of a questionnaire suitable for routine care designed to improve PLWHIV quality of life. • Existing alterations of quality of life were detected in 44% of the participants. • The main detected alterations pertained to sleep, sex life and emotional well-being. • More than one tenth (11%) of these alterations were associated with antiretroviral treatment. Complementarily to immuno-virological control of people living with HIV (PLWH), quality of life (QoL) has become a priority in patient care. OCTAVE® is a self-administered questionnaire comprising 42 questions categorized in eight items: HIV treatment, mental & physical health, sleep, sexuality, emotional well-being, comorbidities and social/professional life. It was developed for use in routine clinical practice, the objective being to identify possible QoL alterations in people living with HIV. Outcome Thirty-nine physicians completed the survey, and 380 PLWH filled out the self-administered questionnaire. All in all, QoL alterations were detected in 44 % of respondents (mean 2.1 (SD = 1.2) per PLWH). For physicians, these findings prompted planned clinical interventions in 70 % of PLWH, predominantly regarding sleep, sexual health and emotional well-being. Of note, 11 % of the reported QoL alterations were attributed to antiretroviral therapy. In routine clinical practice OCTAVE®, appears to be an effective means of detecting QoL impairments in people living with HIV, and it is likely to reinforce clinical management of potential QoL issues.

Source: Infectious Diseases Now

DOI: 10.1016/j.idnow.2025.105216