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Unlocking the Neurogenic Potential of Enteric Glial Cells for Hirschsprung Disease Therapy

Year: 2025
Type: article
Abstract: sponsorship: This study was funded by the National Health and Medical Research Council Medical Research Future Fund and National Stem Cell Foundation Australia. Klaas Van Mechelen was funded by a PhD Fellowship Fundamental Research (11K8523N) and Travel Grant (V465223N) from the Research Foundation Flanders (FWO) and received support from the KU Leuven Global PhD fellowship. Pieter Vanden Berghe is supported by a REACH grant (Reach Hirschsprung Foundation) . Marlene M. Hao was funded by an ARC fellowship (DE190101209) and the National Health and Medical Research Council (2021360) . Lincon A. Stamp was funded by NSCFA, and National Health and Medical Research Council Medical Research Future Fund grants (2009049, 2032801) . (National Health and Medical Research Council Medical Research Future Fund|2009049, National Health and Medical Research Council Medical Research Future Fund|2032801, National Stem Cell Foundation Australia|11K8523N, National Stem Cell Foundation Australia|V465223N, Research Foundation Flanders (FWO), KU Leuven Global PhD fellowship, ARC fellowship|DE190101209, National Health and Medical Research Council|2021360, REACH grant (Reach Hirschsprung Foundation), NSCFA, National Health and Medical Research Council Medical Research Future Fund|2009049, National Health and Medical Research Council Medical Research Future Fund|2032801)
DOI: 10.1016/j.jcmgh.2025.101693
Authors: Klaas Van Mechelen, Jing Zhao, Madeleine R. Di Natale, Linxuan Jiang, David K. Lai, Hui Yu, Matilde Oviedo Querejazu, John B. Furness, Pieter Vanden Berghe, Marlene M. Hao, Lincon A. Stamp
Institutions: The University of Melbourne, KU Leuven, Qingdao University, Affiliated Hospital of Qingdao University, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an Jiaotong University
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,430
Funders: Francis Crick Institute, Fonds Wetenschappelijk Onderzoek, KU Leuven, National Stem Cell Foundation of Australia, Australian Research Council, National Health and Medical Research Council
Awards: Characterization of short- and long-distance neuronal circuits in the enteric nervous system and their specific defects in Hirschsprung’s disease using advanced microscopy and stem cell technology, A gut feeling about new therapies for glioma treatment: lessons from the enteric nervous system, G2266712488, G3019806577, Genes underlying enteric neuron subtype differentiation, G6124179085
OpenAlex ID: W4416866536
FWCI:
Cites: 25
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