Correlation of 3D Echocardiography With Cardiac MRI in Patients With Acute Left Ventricular Dysfunction in the Age Group of One Month to 18 Years
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objectives The objective of this study is to evaluate the correlation and agreement between three-dimensional echocardiography (3D-ECHO) and cardiac magnetic resonance imaging (CMR) in children with acute left ventricular (LV) dysfunction, specifically assessing end-diastolic volume (EDV), end-systolic volume (ESV), and left ventricular ejection fraction (LVEF) and to identify any associated systematic measurement errors. Methods An observational cohort study was conducted in New Delhi, India, over a period of 18 months from June 2021 to November 2022. A total of 16 children aged one month to 18 years with acute myocarditis or new-onset LV dysfunction were enrolled. Clinical details, laboratory parameters, echocardiography, and CMR findings were recorded. Correlations were assessed using Pearson's coefficient, and agreement was analyzed using Bland-Altman plots. Results A very strong positive correlation was found between 3D-ECHO and CMR for LVEF (r = 0.887; p < 0.0001). EDV and ESV also showed strong correlations between 3D-ECHO and CMR (r = 0.906 and r = 0.903, respectively). However, the Bland-Altman analysis revealed that 3D-ECHO consistently underestimated EDV (mean difference = -18.86; p = 0.034) and ESV (mean difference = -21.77; p = 0.014) compared to CMR, while LVEF showed good agreement (p = 0.619). Conclusion 3D-ECHO demonstrates strong correlation with CMR in assessing LVEF in children with acute LV dysfunction and may serve as a reliable bedside tool for systolic function evaluation. However, its underestimation of EDV and ESV highlights the continued role of CMR as the gold standard for precise volumetric assessment.
Source: Cureus
DOI: 10.7759/cureus.98246
Authors: Varsha Shrivastava, Deen Dayal Nagar, Yamini Batham, Amit Kumar
Institution: Fortis Escorts Heart Institute
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416867649