BER-Ago: A simultaneous detection and inhibitor screening platform for multiple base excision repair proteins
Year: 2025
Type: article
Abstract: • BER-Ago was proposed to detect four non-nucleic acid targets simultaneously. • BER-Ago assay could be repurposed to evaluate and screen potential inhibitors for four BER proteins. • BER-Ago offers a new insight into the developments of Ago-based tools for biosensing and therapeutic applications.
Authors: Sheng Ding, Ju Chen, Jing Li, Ting Zhu, Wenyue Jia, Shiqi Xiao, Jin Yang, Dianxiang Lu
Institution: Chengdu University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,950
Awards: G2433667139, G6834030020, G8830061382
OpenAlex ID: W4416867992