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Successful treatment of pulmonary lymphatic perfusion syndrome with lymphatic intervention embolization: a case report

Year: 2025

Type: article

Abstract: Pulmonary Lymphatic Perfusion Syndrome (PLPS) is a rare condition characterized by abnormal lymphatic drainage into the lungs, leading to symptoms such as chyloptysis and chylous effusions. We report a case of a 54-year-old male with PLPS who presented with persistent cough, milky sputum, and pericardial effusion. Following initial misdiagnosis and ineffective empirical treatment for a presumed pulmonary infection, a definitive diagnosis of PLPS was established. The patient underwent successful percutaneous thoracic duct embolization, resulting in complete resolution of symptoms and imaging findings at follow-up. This case highlights the importance of considering PLPS in patients with unexplained chylous effusions and the efficacy of lymphatic intervention as a treatment option.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2025.1696594

Authors: Qunxiang Liu, JiaQi Wang, Yingjie Chen, Wei Qin, Ziyang Zhu

Institution: Wuhan Sixth Hospital

Language: English

Topic: Lymphatic Disorders and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801