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“Sweating Kidneys” refers to perirenal effusion as a complication of SGLT2i: A case reports

Year: 2025

Type: article

Abstract: A 76-year-old male, diagnosed with type 2 diabetes one year prior, was prescribed dapagliflozin. Imaging revealed perirenal effusion resembling "sweating kidneys".The exact mechanism of SGLT2 inhibitor-induced perirenal exudation remains unclear, but hypotheses include volume depletion that leads to increased renal capsule permeability, inflammation of urinary infections that extends to the kidneys, and hypersensitivity reactions that cause swelling and fluid exudation.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103282

Authors: Lianghu Chen, Qiong Lyu, Lingjie Xu, Jing Tian

Institution: The Affiliated Yongchuan Hospital of Chongqing Medical University

Language: English

Topic: Diabetes Treatment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160